Top Definition
1) Any uncomfortable or painful swelling or growths associated with female reproductive or digestive organs, i.e. uterine fibroids

2) A female pain-in-the-ass
Cathy: "Sarah, why are you being such a hermorrhoid today?"

Sarah: "Cut me a break, bitch! My hermorrhoids are acting up again!"
by tnunnster October 06, 2010

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