HTD is a common immediate remark in response to learning something about a particular ho (or hoes) that directly defines them as a ho.
Rather than being slander against hoes, HTD is more often a phrase that accepts that hoes will be hoes and that we are powerless to change them.
HTD can be used as a direct diss but it's considered bad form since it's more elegant to just call a ho a ho.
Non-ho: *smacks ho* "Damn HTD..."
Ho: "Sorry, I ate all your chicken."
Non-ho: *sigh* "HTD..."
Similar to an STD, except made up, it is the excuse teachers give for why you can't hug in skool.
Girl 1: Ok bye.
*girl 1 hugs guy one*
Teacher 1: No hugging in school! Do you want to get Arm Herrpies??? It's the most common HTD.
*Teacher 1 and girl 1 walk away in opposite directions*
*guy 2 walks up*
guy 2: wow, Mrs. Teacher 1 is evil.
guy 1: I know there isn't even such thing.