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1.
1. The ultimate insult to be used. Especailly used to finish off an insult battle.

2. A name to call somebody who is a Mother Fucker, and or Piece of shit.

3. Especially used after someone has made you mad, i.e when someone sleeps with ur girlfiend/wife/mother/sister. most commonly used among guys.

(Femine version is Bitchwhoreslut)
Man 1: Dude, he just railed ur sister!
Man 2: That Goddamnmotherfuckingpieceofshit!
by Anonymous1996@holyshit.edu October 10, 2010