2.) The direction of downtown Detroit from wherever you are.
3.) Adverb: Just generally bad.
2.) Guy in Ann Arbor: "Dude, which way's Detroit?", Other guy: *points east* "Fuckwise"
3.) After a hard exam: "That exam fucked me fuckwise!"
2.A person that never forgets to wear a condom while fucking.
3.One step up from a dumbfuck.
JimmyJoeJackson:You FUCK WIT!!BillyBob:YOU...uhhh...ummmm...FUCKWISE?
2.Sarah:Make sure you be a fuckwise BillyBob and wear a condom before you slam me.
3.BillyBob:I got fire from my fuck wiper job because, I droped a fuck bomb on my manager.
JimmyJoeJackson:Only a fuckwise can be fired from a fuck wiper job