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one who seems to fuck things up everywhere he goes
After three girls enter your dorm room and begin talking to you, this is what happens after fuckn knuckles enters your room:

Girls: hey(to fuck knuckles). do you live here too?
Fuck Knuckles: (does the double arm pump and screams in a loud gay voice, like a white guy trying to be lil john) YEAAAAAH!
Girls: (they promptly leave after giving a look of disgust to fuck knuckles)
Two guys who live in the dorm room: hey fuck knuckles, thanks a lot. (the guys begin to bumrush fuck knuckles and beat the shit outta him for being such a douche)
by Brad Kronik December 31, 2005
General dickhead. See also Fucker, Asshole, Cunt et al.
That's not my wife you stoopid fuck knucle!
by Izzy Stewart April 08, 2003
Can be used to describe a person who is generally a dickhead, or used when something goes wrong.
A) You are such a fuck knuckle

B) Fuck knuckle!
by ~primakat~ August 05, 2005
A derisory term used to denote a particularly ineffective or annoying person or thing.
Refering to a Person: My fuck! What a useless cunt! I declare him to be an absolute fuckknuckle!

Refering to a thing: I'm not eating that processed fuckknucle Subway calls a sandwich!
by Reginald Whattabone March 01, 2005
An idiot, a dumb person.
Wow jones was a fuck knuckle to jump off that roof!
by Hayden The Sexy March 05, 2006
complete idiot
you know that fuckknuckle who got caught trying to break in to the police station
by John June 10, 2003
Similar to definition 1 for Fuck Nuts
Specifically a name for somebody you know and despise in one way or another.
"Have you met Wendy's new boyfriend Eric? Man, what a fuck knuckle that guy is!"
by Simonator May 04, 2006
Brick-like intellegence coupled with new levels of arse-holiness.
My boss is a real fuck-knuckle
by morningwood faerie February 05, 2003