Top Definition
It can be used as a noun, verb, or classification. It's a miss calculation. If you commit an act which is FUBAR, that's a Code Forty-Six, or the offender can be called Agent Forty-Six. In other words this miscalculation has led to some sort of failure.
Two dudes are jogging in Central Park and one avoids the horse crap while the other runs thru it. He just Forty-Six'd his run.

The Pediatrician just asked an RN to give this baby Tylenol and an assistant jumped in and gave Penicillin. Agent Forty-Six strikes again.
by Finsterbaby69 June 21, 2011
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