A self-absorbed, vile, cum-chugging evil bitch who is particularly unphased by being called a "cunt." (See definition for fluffer.) The term fluffer-cunt is more degrading and insulting because it implies that not only is the woman a complete dumpster fire vile-vag whorebag, but apparently she is only useful for preparing someone else to get laid.
The boss is out of the office again? Well when that fluffer-cunt gets back, tell her I quit!