Top Definition
An humorous disease in the brain or emotions when you think your family is falling apart.

A self-paranoid state of guilt where you imagine you're the cause of your family members falling apart all around you.
Howie, a self-paranoid family member, believes he's the sole cause of his families demise and therefore has come down with a severe case of familyitis.
by Jake the Baker September 03, 2011

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