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1.
Similar to "Down to Fuck," DTBF means "down to butt fuck." As in willing to engage in anal pounding, sticking it up the poopenschaft, butt fucking, ramrodding (holy shit that is a real word), buttsecks, whatever you prefer.
She wants me pretty bad, she's even DTBF.

Big Gay Al is DTBF with any man.

dtbf? y/n/m
by Old Gregg's Mangina November 09, 2008
 
2.
abbreviation for "down to be friends", as opposed to "down to fuck". often confused with "down to butt fuck" - make sure you distinguish which one you're talking about!
at first i was totally dtf him... but then i realized he was gay, so now i'm only dtbf - down to be friends.
by beyonce69 July 07, 2010