daughter of a bitch; a male would be known as a SOB (son of a bitch). DOB is a word that is most commonly directed towards a female that says something hurtful, idiotic, or just plain mean to another person. (pronounced DEE-OH-BEE)
marissa: haha fran i stole your boyfriend!
fran: you DOB! how could you betray me like that?! i thought you were my friend!