Top Definition
Extreme dry mouth that follows smoking marijuana.
"That blunt just gave me the worst cotton chops I have had in a while, we need to get some water"
by old man withers August 16, 2006
1 more definition
When after smoking large amounts of pot your mouth becomes dry and pasty.
Dat dooby gave my ass some serious cotton chops.
by JustR December 31, 2009

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