When the act of adoption or not knowing family tree, results in finding out your related to someone you've preformed sexual acts with.
Mom: I don't want you seeing her anymore!

Son: NO! I WONT! I LOVE HER!

Mom: So do I, shes my Niece!

Son: OH MY GOD! WHAT THE FU@K!

Oops-cest isn't always your faul! Ewww!
by RickySTEEZ December 7, 2009
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When two actors/actresses play siblings in one or more movies and love interests in another/other movie(s).
"Did you know Shailene Woodley and Ansel Elgort are brother and sister in Divergent and like dating in Fault In Our Stars?"

"What?! That's cinema-cest."
by ChubChub2000 October 25, 2014
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The act or occasion of becoming romantically or sexually involved with a co-worker(s).
Now that Ben and Jamie are seeing each other, we have a serious case of work-cest on our hands.
by GennyTrent January 6, 2010
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Medical students being absolute whores during what little time they have to engage in social activities and sleeping with anything that has a pulse and is bipedal.

As medical students will only socialize with one another and invariably only talk about medicine/ people they have slept with in medicine when they do; invariably they end up only sleeping with one another/interns/residents/NCHDs.

The latter can be quiet dangerous as sleeping with someone who is in a position of authority in your medical school is a "breach of ethics", alas this is seldom recognized when blood alcohol levels are elevated.

Types of medical students who do not partake: null set

The Royal College of Surgeons in Ireland recently published a paper on lighting levels and observer perceived levels of overtly sexual behavior at a city centre nightclub in Dublin. It found that increased lighting levels decreased sexual behaviors. Should they hope to implement these findings at future events; the student body will be displeased and will launch complaints.

Really medical students engage in promiscuity to make their lives a little brighter. I mean who wants to study 60 hours a week for 4/5 years and end up in a shit pile of debt at the end of it?
OMFG - I think I've slept with five people in school with us this semester. I'm such a whore.

Na! You're actually grand. The five people aren't in the same social circles, everyone will still think you are a gay virgin, don't worry!
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Aren't you gay?

Yes, why is that an issue?

That's a girl you've just slept with.

Really? Hopefully I'll do better next time.
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What does it take to be the class slut this year?#

Sleep with 45/60 people in the class. Sorry babes I'm already there. I love med-cest
by thehornymedstudent January 7, 2012
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When one member of an academic department at a university hooks up with another member of the same department.

Considered slightly incestuous because often members of the same department are often an insular social group that work, hang out and often live (roommates) together. Can also lead to a degree of nepotism.

On the other hand, can be quite common or even encouraged due to the lack of interaction with non-members of the department.
If you are going to take time away from your studies for a love life, make it department-cest so you don't get too distracted. Lab or office-cest is off-limits though.

Did you hear Mike and Sally are shacking up? Department-cest!
by Mike4587 November 19, 2010
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Adapted from the word incest. The term for the antics of a group of closely socially affiliated persons who frequently and casually engage in sexual activity with each other, often simply out of boredom. These people are usually members of cliques that are founded on the concept that non-members are not good enough to speak to, let alone date. People who engage in clique-cest often believe that this behavior has no effect whatsoever on the relationship of each member of the group to all other members of said group. This often turns out to be a false belief, or else simply denial, as jealousy eventually becomes an issue forcing the group apart.

In contrast, this is usually not used to describe actually having had a serious romantic relationship with more than one member of a clique you belong to over an extended period of time. The term may apply if these interconnected romantic relationships put a strain on the clique because of jealousy or general awkwardness.
Non-Clique Member #1: "So Amber slept with Kyle last week, Kyle slept with Stephanie the week before, Nicole made out with Bryan a few days ago at that party, and I heard Kyle is going over to Amber's tonight when her parents leave for the weekend. Creepy."

Non-Clique Member #2: "What is with the clique-cest going on in this school? It's disgusting. Well, at least they're only sharing that nasty chlamydia infection with each other. They think they're too good for the rest of us, but I wouldn't touch any of them with a ten foot pole..."
by Reicheru October 3, 2007
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When the die hard kingdom hearts fans ship together the characters Sora, Roxas, and Ventus.
"What the fuck is this One-cest? You can't make Sora, Roxas, and Ventus have a threesome. They're the same person!"
by I'm going to Kashoot myself January 7, 2019
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