An STD contracted from a woman.
This is a reference to the singer/songwriter Bruce Cockburn
I should never have played hide the sausage with that skank. She gave me the Bruce!
by D. Money March 2, 2008
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Bruce is slang for Marijuana (weed). It is a shorter version of "Bruce Banner" which is used as slang for the drug since it is the name of The Incredible Hulk who is big and green.
The most credited reference is from a rap lyric in Dr Dre's "Some L.A. Niggaz" from King T's verse which goes:

"I'm comin 'Straight Outta Compton' with a loose cannon
Smoke big green, call it Bruce Banner"

Hey man, I'm about to go out back and talk to Bruce.

Anyone seen Bruce around?

by Deacon D May 2, 2007
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Basically the sole meaning of a bro who is so chill, savage, and fucking cool that he out bruces everyone when he walks into a room. Hell outsmoke the stoners, throw some sauce with the boozebags, and bag the finest broads. Do not fuck with this type of man...
Losers always complain about there best, and winners go home and bang the prom queen, thats fuckin bruce as fuck.
by onechillbruce November 5, 2011
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verb. To go on a bender of consuming Girl Scout Cookies, usually multiple boxes a day for several days. The appropriate unit for brucing is in "boxes".
"Last week was rough. I bruced half a dozen boxes of Girl Scout Cookies by Wednesday."
by ossavir March 15, 2017
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Bruce is a name usually given to a male/boy/man. Unfortunately negative homosexual stereotypes are connected to the name "Bruce" from media outlets in the 1980's and 1990's as flamboyantly gay male characters. Note: there is nothing wrong with being homosexual or whatever a person chooses to be - but to assume a person is gay based on their name (having a sense of humor about it isnt bad as long as your not hurting the unfortunate person named Bruce). I believe time is working to switch the "Bruce stereotype" to where it will become worthy of Batman once again.
"Hey, that guy over there is pretty cute I wonder if he is single?" "No Lara, his name is Bruce I'm pretty sure he is Gay"
by FactBasedEvidence September 25, 2019
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