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Big Four 

Usually relates to the "Big Four" Grunge bands of the early '90s.
The Big Four are:

Soundgarden
Pearl Jam
Alice in Chains
Nirvana

Even more interesting, they all come from Seattle
"The Big Four were pioneers for the Grunge genre, not to mention, they just plain kick ass!"
Big Four by GrrTigerMonster April 8, 2009

Big Four 

There are four essential items in any mans life: pound the pussy, eat some food, good shit, and a nice nap. Pound. Eat. Shit. Nap.

The big four is when you can hit all those items in a single day. But it only counts when you hit all four. You can't count two eats, one shit, and one nap, as a big four. However, once the four are completed in a single day, you can add on additional items for a Big Five, Big Six, and so on.
Hey Hal, did you get the big four this weekend? No, the old bag wouldn't let me pound!
Big Four by BigJohnson77 December 30, 2015

Big Four 

The Big Four are the largest railroad companies in the United States. The Big Four consists of CSX, BNSF, Union Pacific and Norfolk Southern. Kansas City Southern almost makes it in, but the foamers would never allow it.
John: Man, I saw locomotives from all Big Four railroads today!
Tom: Literally no one gives a shit about your train addiction, John.

big four of grunge 

Alice in Chains, Nirvana, Pearl Jam and Soundgarden
The big four of grunge are better than the big four of thrash.

Big Four of Thrash 

The Four Largely Popular thrash metal bands that formed in the 1980's. These bands dominated the thrash scene.
They were,Metallica,Megadeth,Slayer and Anthrax.

runners up include-
Exodus,Death Angel,Overkill, destruction and Kreator
the big four of thrash were influenced by hardcore music and NWOBHM and went on to inspire nearly all of todays metal. Slayer Alone is said to be one of the forefathers of death metal.

Big Four Of Melodeath 

Big Four Of Melodeath :

In Flames = Metallica
At the Gates = Slayer
Dark Tranquillity = Megadeth
Soilwork = Anthrax

People only like In Flames' early albums
Lots of people like DT the most out of the 4
AtG have one really popular album that influenced a ****load of bands
And none really cares about Soilwork
Bob: In flames is awesome
Tim: Yeah so is the other Big Four Of Melodeath At the Gates, Dark Tranquility, and Soilwork
Bob and Tim: \m/
Big Four Of Melodeath by knixx January 4, 2009