Neighborhood or ghetto depending on context.

It depends on the accent or the contexts of the conversation.
"ey homie lets go to the barrio fool" (the ghetto)

"hola señor este es mi barrio" (not ghetto)
by BigPimppin6906 November 16, 2017
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A spanish word meaning "hood", "ghetto", or "neighborhood".
Yo steve come with me to the "barrios".
by EgoMasterVirtue November 26, 2008
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Wilkes-Barre, Pennslyvania
Wilkes-Barrio, Pennslyvania
Since no one actually knows how to pronounce "Wilkes-Berry", "Wilkes-Bar", "Wilkes-Bar-ray" or "Wilkes-Bear", referring to this northeastern Pennsylvania city simply as "the barrio" may avoid a fist fight. Barrio is the Spanish word for neighborhood.
Me and my peeps saw ya at Public Square in the Barrio.

The Barrio has the best Haluski and Perogies, hayna?

That Wilkes-Barre Scranton penguin fan is from the Barrio, hayna?

The urban planning in the Barrio is thus: church, bar, church, church, bar, crackhouse, university, bar, church, bar.
by coal miner's daughter September 18, 2006
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a word that means a dirty, mostly mexican neighborhood
"Man, poor dirty mexicans sure filled up that neighborhood quick"

"Yeah man, it's just another barrio now"
by garrison, mrs.garrison April 16, 2009
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The act of shoving a barracuda up one's anus while simultaneously eating a berry.
Man, I saw your mom pull a barrios last night. It looked delicious! mmmmmm
by Jason Dmitri March 22, 2005
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The act of shoving a barracuda up one's anus while simultaneously eating a berry pie.
Man, I saw your mom pull a barrios last night. It looked delicious!
by Jason Dmitri March 22, 2005
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