To diminish or demote someone's social status explicitly through public humiliation and/or constantly undermining their views by another person or through ones engagement in destructive habits.
Everyone thought this new girl was soo hot and cool till Jen anusafied her, now no one wants to hang out with her.

That dude was soo cool in high school till he crossed path with heroine, it totally anusafied him.
by ZDaemon January 16, 2013

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