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A short form of Assassin's Creed: Brotherhood, a historical fantasy third person action-adventure video game developed by Ubisoft Montreal. Also sounds like a crude sexual reference for the uninformed.
Played some solo ASSBRO last night. Ya know, to practice.
by NotScottKurtz November 23, 2010
Basically friends with benefits, but for homosexual men.
Gay guy 1: So Brad and I are screwing every night now.
Gay guy 2: Are you guys dating?
Gay guy 1: No, he's afraid of commitment. We're just assbros.
by Canopenerdude December 01, 2013