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1.
AFU
Short for "All Fucked Up". Meaning usually some thing or situation that is messed up, broken, disorganized, or failed.
We can't take my car, I got in a wreck and it's AFU.

After the earthquake the subway was AFU.
by leshrack March 15, 2003
 
2.
AFU
Means "Almost Fucked Up"
Bob almost had a car crash
Bob: "AFU!"
by CarlosG&JavierM April 15, 2008
 
3.
All Fucked Up
The directions for this project won't work; they're A.F.U.
by CaseyOC October 05, 2008
 
4.
"All Fucked Up". When something has been totally messed up. Also see SNAFU
"After breaking his wrist, his pool game is A F U"
by Matkowitz April 05, 2008
 
5.
AFU
alt.folklore.urban, the parent site of snopes and a canonical place to check bogus internet stories.
Dude, Obama did not just sell the moon to China. You should check that shit on AFU before you forward it, eh?
by BaronRidiculous July 23, 2011
 
6.
afu
abbreviation; as fuck
It's cold afu *TRANSLATION* It is cold as fuck
 
7.
afu
Short for "Anything For You"
First Person: Thank You Very Much!
Second Person: AFY
Firt Person: How Sweet
by Mdanielsen April 30, 2005