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1.
To express dissatisfaction towards the prefix. Another term for saying you suck.

Ex. Bob2lose- Bob sux, i hope bob dies, bob is a douche.
Ugly people2lose
Poop2lose
Saddam2lose
by Nizzle Sizzle April 10, 2003

Words related to 2lose

2win
 
2.
The oppostie of 2win. See 2win
(bob and joe are fighting) Joe2lose

Cheese suxxorz...cheese2lose

flat tits2lose
by Nizzle Chrizzle Shizizzle April 13, 2003