Top Definition
To express dissatisfaction towards the prefix. Another term for saying you suck.

Ex. Bob2lose- Bob sux, i hope bob dies, bob is a douche.
Ugly people2lose
Poop2lose
Saddam2lose
by Nizzle Sizzle April 10, 2003
1 more definition
1 Word related to 2lose
The oppostie of 2win. See 2win
(bob and joe are fighting) Joe2lose

Cheese suxxorz...cheese2lose

flat tits2lose
by Nizzle Chrizzle Shizizzle April 13, 2003

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