Commonly used as a farewell in conversation.

(Represents the two fingers held up for the common peace symbol)
"Gotta go, 2up."
by maanizza January 08, 2004
Top Definition
when passing a joint around you take 2 drags, then pass it on
Oi johno light up were doing 2 ups
by ghosting14414 April 20, 2009
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