A cultural spreading of an obsessive sickness (which usually strikes young girls or middle-aged mothers) that centers around the Twilight Saga created by Stephenie Meyer. With enough personal self-control, it is possible to heal, but some are forever succumbed and lost. TOD can relate to both the book characters and the portraying actors of the series.

For best possible chances of curing a TOD sufferer, make sure they stay away from all Twilight related merchandise and actors.
Normal friend - Are you alright? You didn't call me yesterday.
TOD sufferer - Sorry, I was reading Breaking Dawn again and I noticed something that was so weird because I hadn't ...
Normal friend - (runs away screaming) She's infected with TOD! Quick, everybody, run!

Fake Doctor Example:
Doctor - I'm sorry, there's nothing I can do. You have been diagnosed with TOD (Twilight Obsession Disease).
Patient - So?
Doctor - It's worse than I thought.
by DiseaseControl March 31, 2010
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the act of pissing off harry potter fans by saying twilight is better than harry potter and giving illegible or very stupid reasons.(for trolling purposes)
troll:lmao harry potter is so stupid its about a stupid asshole.twilight is so much better.
harry potter fan:and how exactly is it better than the best selling and my personal favorite book.
troll:it has vampires and sparkles.need i say more.
harry potter fan:are you retarded
(harry potter vs twilight)
by semi456 November 25, 2010
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The experience one gets at a certain point of energized exhaustion. When the body is starting to shut-down due to late-night/early morning hours, but is being forced to function through a surplus of caffeine intake at regular intervals.

Anyone currently in the Zone will feel the symptoms of weariness coupled with jitteriness, loopiness, possible dizziness, and a distinct feeling of being overwhelmed by whatever it is you are trying to stay awake for. S

pelling as well as communicating will most likely become difficult as well as thinking in general.
I have over 100 calculus problems due tomorrow. Staying up to work on them has thrown me into a serious Twilight Zone of Sleep Deprivation. Why is the computer screen moving?

Dude, I'm tired, but I want to stay up with her. It'll be some crazy twilight zone sleep deprivation, but totally worth it.
by PunkPrinzess September 1, 2009
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The time of night from about 7-10 p.m. in which it is too late to take dayquil and too early to take nightquil without disturbing your sleep pattern.
I was dribbling all over myself last night, but it was in the Twilight Zone of Cough Medicine, so I couldn't do anything about it.
by ker.mudgeon March 22, 2011
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(awkward silence)
"So, have you seen Twilight?"
"Yeah! I love that movie!"

"Hey baby, have you seen Twilight?"
"Yeah, you wanna be my Edward Cullen?"
by Anna Graham October 5, 2009
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