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A warcraft custom game, huge fan base. also believeed to have started the word pwned. stands for defense of the ancients.
lets run some dota.
DOTA by cris March 15, 2004
A Game where people usually troll around like retards, feeding enemy team and or just being a faggot
Damn, lets go play some Dota I want to troll badly.
Dota by jerome has a black penis January 1, 2015

no one has ever done this in the history of dota 

"No one has ever done this in the history of dota" was a particularly spicy meme from back when DOTA was relevant. Said by an official commentator of a DOTA championship after witnessing a particularly impressive play by one of the participants.

Generally used as a sarcastic meme if used at all, or used in montages of games which are not DOTA, for the meme potential.

"No one has ever done this in the history of dota" is one of the more difficult memes to pull off as it isn't as well known as many other memes. Main audience is gamers and montage watchers.
*during Widowmaker Overwatch montage* *teamkill*
(Screen freezes after the specific play is shown, and the screenshot is displayed in monochrome. Meme audio proceeds to play)

"No one has ever done this... No one has EVER done this in the history of dota!
a dead game that no one plays
Do you know a dead game?

Yeah,DotA 2
DotA 2 by Janev July 6, 2018

Daddy Dota 

Tamer of e girls, master of the doxes, greatest of the ddosers and the biggest autist.
claims to have 135iq, thinks 5'4 is the optimal height for males
sucks poppychulos cock
father of fancy
abuses benzos
eats ass with teeth
hey man u see dat boi Daddy Dota? he a real nigga dont wanna fuck wit him on my mama he crazy wit that virtual llama
Dota the god will fuck your mother be warned.
Daddy Dota by kingki22 January 2, 2019
drunk off their a**.
(usually you weren't there to drink.)

dota is a way of saying you weren't there to get drunk
or wasted which they both mean to be intoxicated. you leave and come back
they're drunk or high, ur not. ez az that.
me:yo man i had 2 bounce out early! why'd they did they all get dota with out me?

other guy:man, f u! i aint wait'n 4 u 2 get back to drink!
dota by jclyja October 13, 2006