to pop an illegal pill (A drug)
Imma pop off this ecstasy before we go in the club!
by meat rack January 24, 2008
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Purposely getting excited after you lose to throw off the person who won.
IBDW did a reverse pop off to Hungrybox, confusing the fuck out of him.
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To get carried away in one's speech, usually in regards to talking about someone else or some action one is going to do. Basically talkin' mess taken too far.
After a few too many drinks at the party last night, Joe really started to pop off at the mouth. First he started talking about my physique, then about how he could beat me in a fight.
by Dann326 November 29, 2015
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"We could pop off on this"
by SophiG May 1, 2018
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when one of your best friends/friends says pop off sis it means that you ‘slayed’ or ‘worked it’
damn girl........pop off sis’
by __xoxmiaxox__ June 10, 2020
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A positive response indicating that you are doing well, often given in reponse to the question "How's your babyhead?"
Person 1: "Say girl, I haven't seen you around in awhile. How's your babyhead?"
Person 2: "Popped-off, my man. Popped-off."
by Posthip August 16, 2005
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Cheap liquor. Tastes and smells like rubbing alchlohol. Real easy to get drunk with.
Girl: can i have some?
Guy: yeah sure.
Girl: uugh! what is that?
Guy: pop off.

SHit, pass tha pop off. I can't feel my legs!
by Coach Pfeff August 14, 2006
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