When someone finds out that their friend is trying to hook up with their sister.
1) Calvin got colleened.
2) Calvin got majorly colleened.
3) John.
by TDAAWWGG July 11, 2010
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A disease one can obtain when they’ve been friend zoned/ best friend zoned and still led on by the same Person. This disease is commonly found in the middle/high-school age groups
“Bro she said she loves me and then went out with another guy, I don’t know what to say”

Oh crap, you’ve got colleenitis
by JustAManWithARocketLauncher August 22, 2020
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an amazing person who acts retarded with her dance friends. Another name for, EXTREMELY sexy girl, and amazing dancer.
by Colleen Mac January 30, 2008
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probably the hottest thing to walk the earth. A great gurl that makes everybody happy. She's pretty and smart and overall just really great.
Wow i wish my girlfriend was as good as colleen
by thegreatwallofchina January 25, 2010
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a sexy gal with a hott bod, aka...afiltf *a friend id like to fuck*
heyy, colleen is hott
by shulkabaka January 4, 2008
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1.) An Irish girl.

2.) Femina hibernica. A bipedal, female mammal noted for its beautiful coloring and a siren-like irresistibility. While alluring, its reckless disregard for the safety of itself and others make it one of the deadliest creatures in nature. Despite its penchant for risky behavior, its lifespan may be as many as 100 years. The prey and mate most susceptible to the charms of the colleen is the paisano (Vir italicus), often marked by its distinctive cry of, "WHAT THE FUCK, WOMAN?!" A paisano who mates with a colleen has an average lifespan of 42 years.
Zoologists observed one colleen jogging alone and unarmed in an urban park at 11:00 at night, driving her car at 75 mph on the freeway immediately after a severe front-end accident and taking unlabeled red pills from her medicine cabinet - later identified as morphine - for a headache. Although the colleen survived, her paisano mate suffered a heart attack.
by Paladin Fox August 15, 2008
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a Irish girl who is nice talks fast and could rap and could dance and she is really smart
Girl 1: dang colleen can dance
Girl 2: colleen could also talk fast maybe rap too
Girl 1: I agree about colleen
by docter right February 24, 2017
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