To be really busy at a computer, usually in a frantic manner, as in trying to hit a looming deadline. May have a slightly biased reference to programming or writing, but can relate to any work done on the computer. Refers to the first sex letters on a standard English keyboard.
Nevin: You see Vanessa?
Julius: Yeah...but don't bother her. The magazine goes to the printer in less than an hour and she's all qwerty.