Can mean a couple of things:

The term coined in a TV Show when the season or series reaches its dramatic climax or penultimate finale such as a master plan coming to fruition. The Endgame is usually the most anticipated part of a tv show, it's achieved at the end of a season/story arc and is what the episodes prior has been building up to and is often teased throught, this is known as playing The Long Game.

Endgame can also refer to a ship in a TV Show, so the relationship a character will end up with at the end of the series.
Stelena from TVD is so endgame <3333!!!
by RobotWizard December 21, 2017
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When two people who are shipped eventually end up together :)
John nd liyah will end up in the endgame
by Hehehe 😎😏 February 20, 2018
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Hulk dabs

thor plays fortnite and is very mean to noobmaster69
hulk: Dabs

Kids: Cringing

Endgame ladies
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It means when TV couples stay with each other till the end of the show and become each other one true love and ones last one
1 Damon and Elena are endgame cause they are made for each other
2 I would be mad if Damon and Elena were not endgame
by 101lifehacks January 25, 2018
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A word used to describe your favorite ship on a tv series or movie. Also known as Bughead (Jughead Jones and Betty Cooper) on riverdale.
Me: “omg bugheadis the CUTEST!! They are endgame

Person: “Yes I love them SO MUCH I can’t wait to see more bughead!”
by Bugheadisendgame December 24, 2017
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a universe that´s sandwiched in two words: ¨i am Iron Man¨
Dan: bro did you watch Endgame?
Steve: no nigger, im too broke to afford it
by the needless December 16, 2019
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Endgame is the twelfth studio album by the American thrash metal band Megadeth.
Endgame simply fucks Death Magnetic in its pathetic ass... MEGADETH RULES!
by dethman666 January 23, 2011
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