Basically a phrase meant to piss people off. If you think about it, many words can fit between "U" and "BRO?", with the most common outcome of "UMADBRO?", indeed one of the most annoying phrases in history. Women may be offended by this, most likely due because they are not male, however if you ask something like say "UMADSIS?" it just wouldn´t sound right. Be advised to use "BRO?" instead of "SIS?" to prevent yourself from looking like a total dickhead.
1.
John smells something coming from the bathroom. He knocks on the door.

Sarah: I´ll be out in a minute!
John: UTAKINGASHITBRO?
Sarah: What the fuck?!

2.
Mike: The only thing left to watch is Jersey Shore
John: Uh huh
Mike: I got to admit Pauly is cute
John: UGAYBRO?

3.
Liz: My dog died
John: Feel sorry for ya
Liz starts crying.
John: USADBRO?

Try to make up your own combinations with U‹Insert word(s)›BRO?, but use it in appropiate situations, like the ones above.
by I´mYoGrandpaSoListenUp May 08, 2012
mugGet the U‹Insert word(s)›BRO?mug.
Sorry, we couldn't find: *insert word here*. is an error message the displays upon typing a word that doesn't exist in the world of urban dictionary.
Per1 :hey urban dictionary what does ¤º♡%¥《 mean??¿
urban dictionary : Sorry, we couldn't find: *insert word here*
by Bruh sound #3 February 16, 2019
mugGet the Sorry, we couldn't find: *insert word here*mug.
Used to refer to a past memory.

The phrase can be used with almost any word/words in the English language, and hundreds of words from various other languages.
The *insert word/words hear* times

Mary "Hey do you remember if you left your shoes on the boat yesterday arvo?"

Patrick - "You mean back in The 'boat' times?
by Ninjafleaslayer February 02, 2010
mugGet the The *insert word/words hear* timesmug.

insert any word here...

Used in extremely awkward situation when you need ANYTHING to change the subject.
Julia's Boyfriend: "Have you kissed Julia yet?"
Julia's Crush: "insert any word here..."
by UnderziedPotato December 03, 2014
mugGet the insert any word here...mug.
A phrase used instead of what the fuck or what the hell when you are in the presence of an adult or little child who you dont want to hear you say fuck or hell etc.
Micaela: Aaron I hate you soooo much!

Little Kid Walks In

Aaron: What the (Insert Non-Offensive Word Here)!!!!!
by akararules July 06, 2010
mugGet the What the (Insert Non-Offensive Word Here)mug.