To say something incredibly irrelevant or dumb due to overthinking it or not thinking at all.
"Angelica really joe'd up yesterday when she said "wow! if i lived here I'd be home right now!" It was such a Joe up, so stupid."
by amfbitch May 2, 2017
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All this homework is gonna completely joe up my weekend.
by the93owner January 18, 2011
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Originating from a viral video of a black man named joe shouting "Joe me up" with his fist in the air, joe me up is a parody of dab me up, a semi-popular meme that had originated in discord.
"Hey, do you remember Johnathan he got joe'd up, poor guy."

"Ayo Joe me up brother."

"Bro... Joe me up"
by Murts? February 22, 2022
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actually, the correct spelling is wassup joe, not what's up joe?. The term means how are you not hi, or hello. It did not come from what's up yo. It came from the last 20 years of urban people using the name joe as a term of endearment; the same way you would use, what's up buddy.
wassup joe, I didn't see you on the block today.
by tiqueda u.l. January 21, 2005
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A slang term originating from the west side of chicago Meaning the same as hello
but adding joe on the end. evolved from the slang term "yo" see: yo
When u see one of ur ppl that owe u sum money in the streets,
u b like: "what's up joe?"
by meech November 15, 2004
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Joe Biden Wake Up, Joe Biden Wake Up
This is a message from muhammad to Joe Biden about 9/11, Joe Biden Wake Up
by Vet0z September 8, 2021
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