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A combination of "sexy" and "rezzy". The self mindset of a Native American girl who lives on the reservation. She is overweight, yet wears tight revealing clothes, lots of make up and does her hair up. Meanwhile to everyone else, it is appalling.
At the pow wow:

Bill: Look at her, that is disgusting, her rolls are falling out of those clothes that should be on someone 4 sizes smaller than her.
Betty: Ya, she thinks she is Sezzy.
Sezzy by jdui38dj38wedhj August 3, 2010
Related Words
sezzy Sizzy sezy skezzy sazzy Suzzy Seezy segzy senzy Sezza
1. a spin-off of the word "sexy"
2. beautiful
3. attractive
"Damn that thick bitch is sezzy!"
sezzy by Peace is sezzy March 22, 2008
A word to describe someone incredible sexy typically only used if you are or are talking about a boy named Lucas
Me:Lucas is so cute I’m crushing on him hella
Friend: Oh I know he’s sezzy af
Sezzy by Lilghey July 24, 2019
A snake person,irelavent,annoying and has no life
Sezzy by Numbest. November 28, 2018
A dance step created by a Nigerian dancer called spectacularpreye , SEZZY means sexy only in another funny accent that’s when it is pronounced SEZZY
That’s is a SEZZY (sexy) looking girl.

We all know spectacularpreye is SEZZY
SEZZY by Capitaldancers November 30, 2019
"Sizzy" is the ship name between characters Simon Lewis and Isabelle Lightwood in The Mortal Instruments series by Cassandra Clare.
Person: I don't ship Sizzy, Simon and Isabelle aren't right for eachother.
Entrie Fandom: WHAT DID YOU JUST SAY
Sizzy by Clary Herondale July 25, 2016