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serial: serious. Serial is as serious as serial killers. So serious - more serious than cereal. Not as funny as cereal, but more concerned.
usu. in response: exp:

Richard, I'm pregnant!
Are you serial?
Holy rusted metal batman!
Are you serial?
serial by dueEast June 11, 2006
"What? Are you serial?"
serial by CHOPOPJR November 3, 2003
"Dude, I'm super serial. Why don't you believe me when I say I'm super duper serial?"
Serial by Bryan Castillo January 15, 2008
Short for serial number. Often used for an illegal method of registering a program one does not wish to pay for.
I got a serial for photoshop last night and it worked perfectly.
serial by Invalid H. User April 23, 2003
being very serious; dead serious.
John: "I scored with Kelly last night, it was TIGHT! man!"
Jeff: "You serial?"
John: "Hell yeah!"
Jeff: "With trix?" (aka: you're bullshitting)
John: 'No, I'm for real!"
Jeff: "Dam, mofo! Hell yeah!"
serial by Olgie March 30, 2010
after droppin those six niggas we jus started callin him serial
serial by S. Loc January 7, 2004