Being in the worst situation you could be. Typically used in reference to being physically, mentally, morally/ asthetically, performance-wise, or even theoretically damaged in some way. It is the word when you need to describe the level of damage.
An extremely contagious, fast moving parasitic virus that moves from one host to another. This parasite is a predator who feeds off the host mentally, emotionally, physically and financially. Ridding oneself of this parasite is no easy feat due to the fact that the host has no idea they have been infected until it's too late. One must starve this parasite until it detaches and finds another host to feed off of.