by Christopher June 01, 2006

by tdister December 30, 2007

Someone with HIV or another type of disease. Most often caught sexually. This could include any vast array of sexual diseases or anything that can spread during sexual activities.
Wow, look at that girl over there.
Dude, don't mess with her, I heard she has a heavy case of The Bootie Flu.
Dude, don't mess with her, I heard she has a heavy case of The Bootie Flu.
by T.J. Dubz March 29, 2008

by Lt. Roastabotch August 25, 2005

Some people in the slammer have bootie flu and so probably are seen as less desirable mates to those that do not.
by jeffie james macrow October 17, 2008
