1 definition by prettyboy1000
Real talk. Serious talk. Usually between adolescent teenage boys. On occasion, "Boy to Boy" talk can be among grown men when trying to get each other's serious attention.
Example: You break your ankle jumping over a girl who you were trying to T bag. You scream to your buddy who is laughing and thinks you are kidding, "DUDE! Boy to Boy! I need to go to the ER!".
by prettyboy1000 September 6, 2016