Used in conjunction with a member of family or body party to desribe something ugly, nasty or horrible.
Originally comes from a scene in Scary Movie 2 but it is also widely believed to refer to the wrestler.
If your in a bar and a very ugly girl walks in, one might say "I didn't know Kane's sister came in here"
If something smells very nasty, one might say "Fucking hell this smells like Kane's ass hole!"
If someone is talking to you and they have really horrible teeth, one might say "Dude you got teeth like Kane's uncle!"