1 definition by creampie6969

When faced with this lethal effect, one might experience one or many of the following symptoms:

Loss of breath
Fatigue
Boredom
Nausea
Vommitting
Depression
Diabetes
Confusion

Not knowing if you should feel insulted or not

Sudden mental retardation
Random girl: "I don't know if he likes me or not, he's sending a lot of signals."
Random girl's friend: "Oh no, you're just suffering from The Jesse Effect."
by creampie6969 July 2, 2017
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