in its original definition, hyphie is, in fact, a reference to being railed up on YAYO.
Keak the Sneak explains in the track "Super Hyphie":
In The Cut Alone Fuh Doin My Thizzle
Oohin, Drankin, Throwin Up The Huuuunnneeeeedddddssss!!!
Solo, But On The Low, My Buddy (My Buddy)
Doin Hella Shit At One Time
My Definition Of Hyphie Man Is Thizzin, Sniffin Lines
Im In Da Buildin And Im Feelin Like Yeeeeeeee!!!
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