1 definition by SimpleJack42

The act of mixing methamphetamine with a strong opiate (heroin or fentanyl) to use for intravenous injection
We had to call an ambulance after my buddy did a Catalina Wine Mixer

When Dave did his shot he yelled "Fuckin Catalina Wine Mixer!!), I knew we were all in for a long evening
by SimpleJack42 October 14, 2020
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