1 definition by Nerfer9

Top Definition
A druggie, a not sane person, an idiot, a person who punishes another person unfairly
Student: *FART*
Teacher: Go to the office
Student: Thats not fair, you're a tweaker!

Tommy: Hey, Joe, look at John today, he's like high or something!

Joe: Man, he must be a tweaker!


Crazy guy: Look at the flying donuts!
Insane asylum guard: My god, he is crazy!
Insane asylum guard 2: Man, he's a tweaker!

by Nerfer9 April 27, 2009

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