1 definition by Jennan_the_Mad

The disease responsible for any man needing to become circumcised in adulthood instead of as a baby. Other medical reasons will be cited, but those are obviously all lies employed to cover the embarrassing truth.

Knob rot can be avoided by careful daily cleansing and keeping things safe during sex.
First guy: I was circumcised at 22 because my foreskin wouldn't retract properly.
Second guy: A likely story. Admit it - you had knob rot!
Third guy: Three words, dude - soap. And. Water. Keep it clean next time!
by Jennan_the_Mad February 8, 2008
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