The effect of a common frat prank involving picking up one's own soggy bowel product and coloring a sleeping victim's mouth labes with it, making them look like they are wearing special bile-infused mouth syrup.
Miller was the victim of a turd lipstickprank last night and didn't realize until his morning coffee, which was a bit more tangy than usual.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.