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A fictitious anti-depressant from the family of Prozac, Paxil, etc. Used mostly by the Notorious B.I.G. and his crew, circa 1996.
From "Mo Money Mo Problems":

"Like thizat, dangerous
on trizack, leave your ass cozak"
trizack by Nima February 14, 2004
Related Words

TWIZACKLED 

You come to , 90% hammered and wasted, after heavy partying and think you are in Arkansas; then you realize that you have never been in or close to Arkansas
We did shit and drank all 3day weekend, by Monday noon I was so TWIZACKLED

that I thought I was camping in the Arkansas house the Clinton's lived in..
TWIZACKLED by Book 'em Dano! February 14, 2021
1) a ho.
2) an individual of such an annoying magnitude that not God himself could preclude you from disliking him/her.
Geez, that guy's a triack!
triack by vonlichten August 31, 2008
Look at my fine trizak mufucka!
trizak by Anonymous June 13, 2003

triznack 

triznack is another word for saying trick.
EX. im tired of your stupid ass triznacks always asking me for money.
triznack by PIMP S. May 17, 2004

Triznack 

My bitch is workin' the triznack.
Triznack by DaSnoopinatorFoSho March 22, 2003