The medical condition known by doctors as diarrhea which comes as a direct result of a late-night McRun.
Max: Holy shit Tim! We shouldn't have gone on that McRun last night!
Tim: What's the matter?
Max: That McRun gave me a NASTY case of the McRuns!!
Tim: What's the matter?
Max: That McRun gave me a NASTY case of the McRuns!!
by Maxwell Dope November 9, 2013
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