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Skizzerin is derived from "scissoring" which is a sexual practice usually done by lesbians. Wherein the practice usually entails the two women positioning themselves so their genitalia can rub together. This connotation of this word has evolved to mean when women cause drama either amongst themselves or those around them.
"Bitches be 'skizzerin'.
by McHuman Deluxe February 24, 2009
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