pyded up Share definition Flag to be in a bitchy, pissy, annoyed, angry or pissed off mood and exibiting an ill attitude. Cristi was all pyded up when I saw her today....guess someone just really pissed her off. pyded up by barefoot professor July 7, 2009 0 0 Get merch Get the pyded up mug. Buy Now — $32.95 See more merch
