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ppsyndrome

aw man i got ppsyndrome again
by CLUMBSY LEMMONS April 7, 2022
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Big pp syndrome

"I was born with big pp syndrome" "nah"
by TheManWithBigPP April 13, 2020
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Small PP syndrome

Usual associated with the name Brandon Crum.
Brandon is the CEO of small pp syndrome
by @Permanett February 8, 2020
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upsyndrome

1. The state of one's PENIS being in a perpetual state of happiness.
"Ever since meeting Caroline, I think Tom has come down with a bout of up-syndrome."

"...It really sucks having your upsyndrome flair up at a gay bar..."

We always thought Susie was weird, then the truth reared its ugly little head -- out of her pants when she was diagnosed with up-syndrome!"

5:00 News Headline:
"Rare condition found in man with up-syndrome -- are two penises better than one?"
by PetShelterPimp May 13, 2005
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upsyndrome

having so much down syndrome that you dont even know what is going on. you must have a lot of downs to be able to get upsyndrome. this is a very rare but life threating disease. but by having upsyndrome you are automatically a playa.
guy 1: is that an upsyndrome over there!?
guy 2: duh. he is so dumb. but he is a boss at the same time.
guy 1: word.
by wordmang222 December 15, 2010
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PP syndrome

PP Syndrome is when your pp shrinks and make a hole in your ballsack.
Man, When i had PP syndrome, and my balls made a hole. it hurt like a tsunami
by MRDuddelnuddel June 17, 2020
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