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When for whatever reason you cannot see.
Most common causes of Karkand Syndrome are :
- Having a glass eye
- Being Blind
- Playing the map 'Strike at karkand' on Battlefield 2
- Having the draw distance set to -200ft
- Dynasty Warriors.
"I hear he got karkand syndrome after running into a wall of spikes"

"Shit , this fog is so bad its like i have Karkand Syndrome"
by Mengzor April 09, 2008
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