1. a name for those who have sexual intercourse with somebody's grandmother.

2. a motherfucker who has earned the title of Great Grand

Motherfucker
"Hey Timmy, go fuck your great grandmother, you greatgrandmotherfucker."

"Dude, ur not just a grandmotherfucker, your a greatgrandmotherfucker."
by southparkisforintellectuals April 29, 2010
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