to "give it toes" simply means to leave. More specifically to go home or somewhere else when the place you are currently has served its purpose or become boring. In personal experience it is acceptable to abbreviate the phrase down to "toes?" when asking somebody familiar with the term.
"I've had enough of this place, let's give it toes."
by Thom Gavin March 11, 2007
by TheGreen October 17, 2008
October 5 is known as national give me them toes day you much give your toes to anyone who asks you so start uncovering those feet
by xXjesus.christXx October 05, 2018