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A play on the word bizerk; combined with the Son of Sam, David Berkowitz to describe a state of insanity. Most effectively used as a verb, but may also be used as a noun.
Ex: Hey, did you see Jimmy go bizerkowitz yesterday after that dude cut him off??

or

Hey, check out Bizerkowitz over there freakin out on the cashier.
by fmbsl April 11, 2009
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