Originating from the phase, “what the fucks the matter with you”, Ahyou is a word you whip out when you wanna ask someone what’s wrong with them. Can also be said as; “AHYOUUU” or simply “you?”.
Friend 1: Yo man I was so trashed last night that I climbed a building and threw a ladder off of it”

Friend 2: AHYOUUUU
by RealNiggaz March 26, 2019
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